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Justine Bruce Selected Research

ASG-5ME

10/2019A phase I study of the antibody drug conjugate ASG-5ME, an SLC44A4-targeting antibody carrying auristatin E, in metastatic castration-resistant prostate cancer.

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Justine Bruce Research Topics

Disease

2Neoplasms (Cancer)
10/2022 - 11/2016
2Fatigue
10/2019 - 11/2016
2Prostatic Neoplasms (Prostate Cancer)
10/2019 - 11/2016
2Diarrhea
10/2019 - 11/2016
1Circulating Neoplastic Cells
10/2022
1Hypoxia (Hypoxemia)
10/2019
1Constipation
10/2019
1Exanthema (Rash)
10/2019
1Hyponatremia
10/2019
1Neutropenia
10/2019
1Abdominal Pain (Pain, Abdominal)
10/2019
1Nausea
11/2016
1Breast Neoplasms (Breast Cancer)
11/2016
1Vomiting
11/2016
1Renal Cell Carcinoma (Grawitz Tumor)
11/2016

Drug/Important Bio-Agent (IBA)

1Peptides (Polypeptides)IBA
10/2022
1Biomarkers (Surrogate Marker)IBA
10/2022
1Immunoconjugates (Immunoconjugate)IBA
10/2019
1auristatinIBA
10/2019
1ASG-5MEIBA
10/2019
1TroponinIBA
10/2019
1monomethyl auristatin EIBA
10/2019
1Tyrosine Kinase InhibitorsIBA
11/2016
1Docetaxel (Taxotere)FDA Link
11/2016
1Prednisone (Sone)FDA LinkGeneric
11/2016
1Abiraterone AcetateIBA
11/2016
1TabletsIBA
11/2016
1Pharmaceutical PreparationsIBA
11/2016
14- amino- 5- fluoro- 3- (5- (4- methylpiperazin- 1- yl)- 1H- benzimidazol- 2- yl)quinolin- 2(1H)- oneIBA
11/2016
1Capsules (Microcapsules)IBA
11/2016

Therapy/Procedure

2Castration
10/2019 - 11/2016
1Immunotherapy
10/2022
1Drug Therapy (Chemotherapy)
11/2016
1Therapeutics
11/2016